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ChemiClean 2g treats up to 300 gallons. It helps clean stains from red, black, blue-green, and methane (bubble) producing cyanobacteria in marine aquariums. It is completely safe for all fish, corals, invertebrates, and nitrifying bacteria in reef systems. It's simple, quick and easy to use. Chemiclean works within 48 hours oxidizing trapped organic sludge and promotes an ideal enzyme balance. ChemiClean will clean stains from red cyanobacteria in aquariums. Aquarium oxygen levels MUST be increased using heavy aeration or large air stone. Turn off UV sterilizer, ozonizer, and remove Chemi-pure, or carbon during treatment. Continue using protein skimmer, although skimmer may require adjustment to prevent excessive overflow. Maintain normal water flow using pumps and power heads. For every ten (10) gallons of aquarium water, dissolve one level scoop (included) of ChemiClean into one cup of water removed from the aquarium. Pour solution with dissolved ChemiClean back into aquarium, dispersing evenly. Successful treatment may take up to 48 hours. After the 48 hour treatment period, perform a 20% water change. Turn on UV sterilizer, ozonizer, and replace Chemi-pure or carbon. Repeat as necessary. ChemiClean can be used monthly as a regular component of aquarium maintenance.